Study links cognitive impairment, dementia to severe risk of Covid-19


Cognitive impairment, dementia are likely to be the risk factors for developing severe COVID-19, according to research from the University of Georgia. The results underscore the need for special care for populations with these pre-existing conditions during the pandemic.

The study was published online in the journal Brain, Behavior and Immunity.

In the study, researchers analyzed data from nearly 1,000 diseases and two specific genes to compare the health profiles of COVID-19 patients with those who test negative, looking for similarities in the patients. COVID-19.

The study drew on data from UK Biobank, a long-term study of over 500,000 participants studying the respective contributions of genetic predisposition and environmental exposure to disease development.

From March, UK Biobank began reporting the COVID-19 status of its participants. The team in the Department of Genetics at Franklin College of Arts and Sciences, led by Assistant Professor Kaixiong Ye and his postdoctoral fellow Jingqi Zhou, quickly connected COVID-19 status to electronic health data.

“We took a no-guesswork approach and the most statistically significant are cognitive impairment and type 2 diabetes,” said Ye, lead author of the study. “At the moment, we don’t know the mechanisms behind these associations, we only know that they are more common in COVID-19 patients.”

Analyzing the genetic factors that make some individuals more at risk for severe COVID-19, the team focused on two genes: ACE2 and TPMPRSS2, known to be essential for the virus to enter human cells. specific genetic variation is more common in the COVID-19 patient, ”he said. The research team also found that variations in genes linked to SARS-CoV-2 infection may be associated with severe COVID-19 that requires hospitalization.

(Only the title and image of this report may have been reworked by Business Standard staff; the rest of the content is automatically generated from a syndicated feed.)

Dear reader,

Business Standard has always strived to provide up-to-date information and commentary on developments that matter to you and have broader political and economic implications for the country and the world. Your encouragement and constant feedback on how to improve our offering has only strengthened our resolve and commitment to these ideals. Even in these difficult times resulting from Covid-19, we remain committed to keeping you informed and updated with credible news, authoritative views and cutting-edge commentary on relevant current issues.
However, we have a demand.

As we fight the economic impact of the pandemic, we need your support even more so that we can continue to provide you with more quality content. Our subscription model has received an encouraging response from many of you who have subscribed to our online content. More subscriptions to our online content can only help us achieve the goals of providing you with even better and more relevant content. We believe in free, fair and credible journalism. Your support through more subscriptions can help us practice the journalism to which we are committed.

Support quality journalism and subscribe to Business Standard.

Digital editor

Source link

Leave A Reply

Your email address will not be published.